Diisobutyldimethoxysilane, a specialized organosilane compound with increasing significance in material science and chemical manufacturing, is identified by its CAS No. 17980-32-4. In many industrial processes, this transparent liquid is an necessary component and performance booster. It has unique properties due to its structure. Chemists and engineers use this silane because it can change the characteristics of materials and is useful in making organic compounds. To use it effectively and responsibly, one must have a solid understanding of its features, uses, and safety procedures. Its chemical characteristics, synthesis, industrial uses, and safety issues will all be thoroughly examined in this article.
Diisobutyldimethoxysilane Chemical Properties
Diisobutyldimethoxysilane CAS No. 17980-32-4 is useful because of its unique chemical and physical characteristics. Two isobutyl and two methoxy groups are bound to a central silicon atom in its structure. The methoxy groups offer a site for reactivity, especially hydrolysis, while the bulky isobutyl groups affect its solubility and steric profile. One important characteristic that enables the molecule to function as a crosslinker or surface modifier is its reaction with water.
It is easy to incorporate into different formulations because it is a clear liquid with a defined density and boiling point. Because of its flash point, it is a combustible liquid that needs to be handled carefully. Because of these characteristics, it is a chemical intermediate that is both sensitive and versatile.
| Property | Value |
| Molecular Formula | C₁₀H₂₄O₂Si |
| Molecular Weight | 204.38 g/mol |
| Physical State | Clear, colorless liquid |
| Boiling Point | 188°C (370.4°F) |
| Density | 0.863 g/cm³ at 20°C (68°F) |
| Flash Point | 62°C (143.6°F) |
| Reactivity | Reacts with water/moisture |
Diisobutyldimethoxysilane Weight and Molecular Formula
Diisobutyldimethoxysilane (CAS No. 17980-32-4) has the molecular formula C₄¹H₂₄O₂Si. Its molecular weight is 204.38 g/mol due to its composition. For stoichiometric calculations in chemical synthesis, these basic values are necessary. In order to guarantee precise reactant ratios.
Engineers can determine the necessary loading levels in polymer or coating formulations in industrial applications by using the molecular formula and weight. The formula’s implied structure sheds light on its purpose. Its function in material science is defined by the two isobutyl groups.
Diisobutyldimethoxysilane Organic Synthesis Applications
Diisobutyldimethoxysilane is a helpful reagent and intermediate in organic synthesis. Its primary function is as an external donor in Ziegler-Natta catalysis. The isobutyl groups’ steric bulk aids in regulating the polymer’s stereochemistry.
Chemists can apply it to synthetic reactions beyond polymerization. By substituting the methoxy groups, they can produce more intricate organosilane structures. Although other silanes are more frequently employed for this purpose, it can also be used as a precursor for the sol-gel processes that produce silica-based materials. Its use as a specialty reagent emphasizes how important it is to the creation of high-performance polymers.
Pharmaceutical Uses of Diisobutyldimethoxysilane
Researchers are still investigating diisobutyldimethoxysilane for pharmaceutical applications. They may use its silane characteristics as an intermediate in synthesizing complex active pharmaceutical ingredients (APIs) or to modify the surfaces of medical devices. A well-known method for producing hydrophobic or biocompatible surfaces on implants and diagnostic equipment is silanization.
However, a thorough assessment is necessary for any use in a pharmaceutical setting. It is necessary to thoroughly investigate the compound’s safety and effectiveness as well as any byproducts from its reactions, such as methanol from hydrolysis. Biocompatibility testing and adherence to stringent regulatory standards are paramount. At present, its primary value remains in industrial chemical synthesis rather than direct pharmaceutical formulation.
Comprehending the Safety Data Sheet (SDS) for Diisobutyldimethoxysilane
The Safety Data Sheet (SDS) for diisobutyldimethoxysilane provides guidelines for safe handling. It is classified as hazardous to the aquatic environment with long-lasting effects by the GHS (Aquatic Chronic 2). Because of this classification, particular measures must be taken to keep it out of waterways.
Important safety details consist of:
- Precautionary Statements: P501 (Dispose of contents/container in accordance with local regulations), P273 (Avoid release to the environment), and P391 (Collect spillage).
- Data on Toxicity: With an LD50 (oral, rat) of >2000 mg/kg and an LD50 (skin, rat) of >2000 mg/kg, the acute toxicity is minimal.
- Storage and Handling: It should be kept in tightly sealed containers away from sources of moisture and ignition in a cool, well-ventilated area. Handlers are required to wear the proper personal protective equipment (PPE), such as chemical-resistant gloves and safety glasses.
The Industrial Applications of High Purity Silane
A high purity grade of diisobutyldimethoxysilane is necessary for many of its industrial applications. Impurities can negatively affect catalytic processes or the final properties of a material. For instance, in the production of polypropylene, contaminants may contaminate the Ziegler-Natta catalyst or cause flaws in the polymer chain.
The main industrial application is in the synthesis of polypropylene as an external electron donor. Additional possible applications include serving as a crosslinking agent in specialty silicone systems or as a component in specific coating formulations. Because these high-tech applications are sensitive and precise, there is a need for a high-purity silane.
The Synthesis of Diisobutyldimethoxysilane
Usually, a chlorosilane precursor reacts with isobutyl Grignard reagents and methanol to produce diisobutyldimethoxysilane. Dichlorodimethylsilane is a common starting point. Chemists create diisobutyldichlorosilane by reacting this precursor with two equivalents of an isobutyl Grignard reagent (isobutylmagnesium bromide or chloride).
In the subsequent critical step, chemists react this intermediate with methanol, often in the presence of a base such as an amine, to neutralize the HCl byproduct. This methanolysis reaction produces the final product, diisobutyldimethoxysilane. To prevent premature hydrolysis of the reactants and products, chemists must carry out the entire process under anhydrous (water-free) conditions. They usually achieve the high purity required for industrial use through distillation.
Typical Questions and Responses
What is diisobutyldimethoxysilane’s molecular formula?
C₁¹H₂₄O₂Si is the molecular formula.
How should diisobutyldimethoxysilane be handled safely?
You should handle it in a well-ventilated area with the appropriate PPE and refrain from releasing it into the environment. For handling, disposal, and storage, always adhere to the instructions on the Safety Data Sheet (SDS).
What is diisobutyldimethoxysilane’s boiling point?
The boiling point is 188°C (370.4°F) at standard atmospheric pressure.
What are the industrial uses of diisobutyldimethoxysilane?
Its main industrial application is as a catalyst component, or external electron donor, in the synthesis of high-performance polypropylene. Additionally, chemists can use it in material formulations and specialty organic synthesis.
How dense is diisobutyldimethoxysilane?
At 20°C (68°F), the density is roughly 0.863 g/cm³.
