2,2-Difluoroethyl trifluoromethanesulfonate is an essential fluorinated organic intermediate. It helps synthesize trifluoromethanesulfonate esters and fluorinated alkyl triflates, which are crucial to advanced material and medicinal research. It also prepares proteomics-relevant fluorinated sulfonate compounds. Its strong reactivity and stability make it essential for trifluoromethanesulfonic acid derivatives. It also helps synthesize 2,2-difluoroethyl sulfonates, making it important in organic synthesis. Proper handling ensures its safety and efficacy in various industrial applications.
Key Properties of 2,2-Difluoroethyl Trifluoromethanesulfonate
2,2-Difluoroethyl trifluoromethanesulfonate has unusual physical and chemical features that make it useful in many applications. Its 118°C boiling point shows its stability under controlled settings. This makes it suitable for temperature-controlled procedures. Its colorless to light yellow appearance indicates great purity, which is necessary for advanced chemical synthesis.
The fluorinated structure of 2 -difluoroethyl trifluoromethanesulfonate makes it more reactive than other trifluoromethanesulfonic acid derivatives. This characteristic helps it create trifluoromethanesulfonate esters and fluorinated alkyl triflates. These derivatives are widespread in medicinal research and material science, demonstrating the compound’s flexibility.
The capacity to create 2,2-difluoroethyl sulfonates makes 2,2-difluoroethyl trifluoromethanesulfonate unique among fluorinated organic intermediates. These chemicals are essential for proteomics and other specialized fields. Its flexibility with different reaction conditions and capacity to preserve integrity in many environments make it popular with researchers and industrial applications.

Chemical synthesis applications
2,2-Difluoroethyl trifluoromethanesulfonate’s flexibility and reactivity make it essential in chemical synthesis. It is frequently utilized to prepare important pharmaceutical and material science intermediates, trifluoromethanesulfonate esters. These esters enable the production of stable, useful molecules, making them essential in many sectors. The molecule also synthesizes fluorinated sulfonate compounds, which are used to make specific materials and reagents.
Additionally, 2,2-difluoroethyl trifluoromethanesulfonate helps proteomics researchers create new inhibitors and bioactive compounds. Researchers can investigate new drug development and molecular biology routes with its unique features. Its capacity to generate 2,2-difluoroethyl sulfonates, which are essential for researching protein interactions and activities, makes it even more important.
Fluorinated organic intermediate 2,2-difluoroethyl trifluoromethanesulfonate facilitates the creation of trifluoromethanesulfonic acid derivatives and fluorinated alkyl triflates. These compounds are valued for developing high-performance materials and catalysts. Its versatility makes it important in current chemical synthesis and research.
Safety Precautions for Handling
Handling 2,2-difluoroethyl trifluoromethanesulfonate demands special safety procedures due to potential dangers. Acute poisoning can result from inhaling or ingesting this chemical. Thus, users must avoid vapors and ingestion. Safe labeling and storage reduce handling dangers. Users should also keep the chemical away from incompatible substances to avoid reactions.
Wear chemical-resistant gloves, safety eyewear, and lab coats to reduce dangers. Proper ventilation prevents vapor buildup in tight spaces. All 2,2-difluoroethyl trifluoromethanesulfonate activities should be done in fume hoods or well-ventilated rooms. These steps make the workplace safer and reduce exposure.
Laboratory personnel should dispose of 2,2-difluoroethyl trifluoromethanesulfonate and its residues according to approved protocols. They must clean spills immediately with absorbent materials and dispose of the waste following local requirements. Accidentally exposed people should have easy access to eyewash facilities and safety showers. These procedures ensure compound safety and integrity throughout usage.
Storage Tips for 2,2-Difluoroethyl Trifluoromethanesulfonate
2,2-difluoroethyl trifluoromethanesulfonate must be stored properly to avoid deterioration. This compound should be stored in a cool, dry, well-ventilated place away from direct sunlight and heat. To prevent moisture and air damage, use airtight containers made of appropriate materials. In a chemical storage cabinet, inadvertent contamination is reduced.
Users must avoid reactive substances and oxidizers when handling 2,2-difluoroethyl triflate and related fluorinated sulfonate compounds to prevent deterioration. Separating these chemicals from incompatible substances decreases reactions. Maintaining a steady storage temperature preserves the compound’s chemical characteristics, preserving its versatility.
Regular storage and container inspections help spot hazards early. To ensure safe handling, 2,2-difluoroethyl trifluoromethanesulfonate labels should list its constituents and risks. Preventing contamination requires rapid cleanup with appropriate absorbent materials after spills or leaks. These storage instructions prolong and protect the substance, making it suitable for chemical synthesis and other specialised applications.
Frequently asked
Chemists widely use 2,2-difluoroethyl trifluoromethanesulfonate in chemical synthesis because of its stability and reactivity. They primarily use it to produce trifluoromethanesulfonate esters, which serve as important intermediates in pharmaceuticals and material science. These esters enable the creation of sophisticated molecules with improved chemical characteristics, making them essential in industrial processes. Chemists also use the substance to synthesize fluorinated sulfonate compounds required for producing specific reagents and materials.
2,2-difluoroethyl trifluoromethanesulfonate has a boiling point of 118°C, indicating thermal stability under regulated conditions. This feature makes it suitable for precision temperature-controlled processes. Inhaling or swallowing it might be hazardous, therefore users must handle it carefully. Direct exposure to fumes or inadvertent intake can cause acute poisoning, requiring protective gear and ventilation.
In proteomics research, 2,2-difluoroethyl trifluoromethanesulfonate helps build new inhibitors and bioactive compounds. Its 2,2-difluoroethyl sulfonate formation makes it important for protein interactions and molecular biology research. Safety precautions assure its safe and effective usage in these applications.